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Shiow-Lin Pan Selected Research

denbinobin

1/2013Denbinobin induces human glioblastoma multiforme cell apoptosis through the IKKα-Akt-FKHR signaling cascade.
7/2011The inhibition of angiogenesis and tumor growth by denbinobin is associated with the blocking of insulin-like growth factor-1 receptor signaling.
5/2009Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells.
11/2008Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells.
2/2008Denbinobin induces apoptosis in human lung adenocarcinoma cells via Akt inactivation, Bad activation, and mitochondrial dysfunction.

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Shiow-Lin Pan Research Topics

Disease

75Neoplasms (Cancer)
06/2022 - 02/2003
13Prostatic Neoplasms (Prostate Cancer)
12/2021 - 02/2003
12Colorectal Neoplasms (Colorectal Cancer)
11/2019 - 07/2008
11Hepatocellular Carcinoma (Hepatoma)
01/2017 - 03/2005
8Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2020 - 07/2003
7Neoplasm Metastasis (Metastasis)
01/2019 - 11/2007
6Breast Neoplasms (Breast Cancer)
01/2019 - 06/2004
5Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
06/2022 - 12/2018
5Lung Neoplasms (Lung Cancer)
07/2021 - 07/2007
5Leukemia
05/2021 - 01/2012
4Carcinogenesis
10/2020 - 08/2012
4Body Weight (Weight, Body)
01/2017 - 01/2012
4Hyperplasia
01/2016 - 06/2003
4Hypoxia (Hypoxemia)
09/2015 - 09/2009
4Adenocarcinoma of Lung
08/2012 - 02/2008
3Cardiovascular Diseases (Cardiovascular Disease)
12/2020 - 09/2009
3Multiple Myeloma
01/2020 - 11/2017
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2019 - 08/2013
3Vascular System Injuries
01/2016 - 06/2003
3Renal Cell Carcinoma (Grawitz Tumor)
01/2015 - 01/2012
3Inflammation (Inflammations)
01/2010 - 02/2007
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/2018 - 07/2015
2Ovarian Neoplasms (Ovarian Cancer)
01/2017 - 01/2016
2Neointima
06/2012 - 01/2006
1Hematologic Neoplasms (Hematological Malignancy)
06/2021
1Stomach Neoplasms (Stomach Cancer)
06/2021
1Reperfusion Injury
12/2020
1Infarction (Infarctions)
12/2020
1Ischemia
12/2020
1Disease Progression
10/2020
1Alzheimer Disease (Alzheimer's Disease)
04/2020

Drug/Important Bio-Agent (IBA)

12Histone Deacetylase InhibitorsIBA
06/2021 - 12/2011
12Pharmaceutical PreparationsIBA
05/2021 - 05/2005
11Proteins (Proteins, Gene)FDA Link
07/2021 - 09/2009
7Histone Deacetylases (Histone Deacetylase)IBA
06/2021 - 01/2012
7Antineoplastic Agents (Antineoplastics)IBA
10/2020 - 07/2007
7Hormones (Hormone)IBA
08/2014 - 10/2005
6Phosphotransferases (Kinase)IBA
06/2022 - 07/2011
5TubulinIBA
08/2015 - 06/2004
5denbinobinIBA
01/2013 - 02/2008
4CaspasesIBA
05/2021 - 02/2008
4Histone Deacetylase 6IBA
12/2020 - 05/2014
4Biological ProductsIBA
10/2020 - 02/2007
43- (1- benzenesulfonyl- 2,3- dihydro- 1H- indol- 5- yl)- N- hydroxyacrylamideIBA
01/2019 - 01/2012
4dendrophenolIBA
01/2017 - 07/2008
4NF-kappa B (NF-kB)IBA
01/2012 - 10/2005
3EnzymesIBA
06/2021 - 11/2014
3Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
05/2021 - 08/2013
3FlavonoidsIBA
01/2021 - 06/2012
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2020 - 08/2013
3VorinostatFDA Link
07/2015 - 12/2011
3Histones (Histone)IBA
07/2014 - 12/2011
3lissamine rhodamine B (sulforhodamine B)IBA
05/2011 - 10/2005
3IndazolesIBA
01/2006 - 03/2005
2AfatinibIBA
07/2021 - 03/2020
2Eukaryotic Initiation Factor-4EIBA
10/2020 - 09/2015
2Mitogen-Activated Protein KinasesIBA
10/2020 - 04/2003
2B7-H1 AntigenIBA
03/2020 - 01/2020
2Ligases (Synthetase)IBA
01/2020 - 11/2017
2MPT0G211IBA
01/2019 - 12/2018
2Matrix Metalloproteinases (MMPs)IBA
01/2019 - 01/2006
2Doxorubicin (Adriamycin)FDA LinkGeneric
12/2018 - 05/2005
2Vincristine (Oncovin)FDA LinkGeneric
12/2018 - 07/2015
2Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
01/2018 - 01/2016
2Protein Kinases (Protein Kinase)IBA
01/2017 - 07/2008
23,6- bis(5- chloro- 2- piperidyl)- 2,5- piperazinedioneIBA
01/2016 - 08/2013
2Antimitotic AgentsIBA
01/2016 - 02/2008
2YXM110IBA
09/2015 - 09/2013
2compound 21IBA
08/2015 - 10/2013
2matrigelIBA
10/2014 - 07/2011
2Cadherins (E-Cadherin)IBA
07/2014 - 04/2011
2Caspase 3 (Caspase-3)IBA
03/2014 - 02/2008
2Type II DNA Topoisomerases (Topoisomerase II)IBA
01/2014 - 01/2012
2Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2014 - 06/2007
2cryptopleurineIBA
08/2012 - 07/2011
2antofineIBA
08/2012 - 07/2011
2neotanshinlactoneIBA
07/2012 - 03/2010
2CytokinesIBA
01/2010 - 05/2005
2evodiamineIBA
09/2009 - 05/2005
22-phenyl-4-oxohydroquinolineIBA
02/2008 - 06/2007
2bromovulone IIIIBA
08/2006 - 10/2005
2ProstaglandinsIBA
08/2006 - 10/2005
13-hydroxyflavoneIBA
06/2022
1fms-Like Tyrosine Kinase 3IBA
01/2022
1Pargyline (Pargyline Hydrochloride)FDA Link
12/2021
1Hydroxamic Acids (Hydroxamic Acid)IBA
12/2021
1BenzamidesIBA
07/2021
1entinostat (MS 275)IBA
06/2021
1ChromatinIBA
06/2021
1Epidermal Growth Factor (EGF)IBA
03/2021
1triphenyltetrazoliumIBA
12/2020
1Single-Chain AntibodiesIBA
11/2020
1AcridinesIBA
04/2020
1compound 17IBA
03/2020

Therapy/Procedure

20Therapeutics
05/2021 - 05/2008
4Drug Therapy (Chemotherapy)
12/2018 - 01/2010
4Oral Administration
01/2018 - 06/2012
2Radiotherapy
11/2014 - 03/2013
2Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2012 - 01/2010
2Aftercare (After-Treatment)
01/2012 - 10/2005